Lung cancer is a type of cancer that begins in the lungs. Your lungs are two spongy organs in your chest that take in oxygen when you inhale. Over the past years, our understanding of the pathogenesis of lung cancer has advanced impressively. Environmental carcinogens and a gene locus  ‎Etiology · ‎Genetic Susceptibility · ‎CELLULAR AND · ‎PREMALIGNANT. Cancer risk decreases after smoking cessation, but existing initiated cells may progress if another carcinogen carries on the process. SCLC and NSCLC are treated differently because they (i) originate from different cells, (ii) undergo different pathogenesis processes, and (iii) accumulate different genetic mutations.‎Overview · ‎Etiology · ‎Pathogenesis · ‎Classification of invasive.


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The trachea then divides into the left and right bronchi, lung cancer pathophysiology breathing tubes that carry air into the lungs.

The bronchi further branch out into smaller tubes called bronchioles, which end in tiny air sacs called alveoli. The alveoli are responsible for the exchange of the gases oxygen and carbon dioxide between the lungs and the blood.

Lung cancer | McMaster Pathophysiology Review

The nose filters the air during inhalation to prevent large particles from entering lung cancer pathophysiology lungs. Mucus lines the bronchi. Most of these genes are kinasesand can be mutated in different ways, including amplification.

Symptoms such as coughing up blood and unintentional weight loss may prompt further investigation, such as medical imaging. Family history of lung cancer.

People with lung cancer pathophysiology parent, sibling or child with lung cancer have an increased risk of the disease. Complications Lung cancer can cause complications, such as: People with lung cancer can experience shortness of breath if cancer grows to block the major airways.

Lung cancer can also cause fluid to accumulate around the lungs, making it harder for the affected lung to expand fully when lung cancer pathophysiology inhale.

Lung cancer can cause bleeding in the airway, which can cause you to cough up blood hemoptysis.

Adenocarcinoma of the lung

Lung cancer pathophysiology bleeding can become severe. Treatments are available to control bleeding.

Advanced lung cancer that spreads to the lining of a lung or to another area of the body, such as a bone, can cause pain.


Tell your doctor if you experience pain, as many treatments are available to control pain. Fluid in the chest pleural effusion.


Lung cancer can cause fluid lung cancer pathophysiology accumulate in the space that surrounds the affected lung in the chest cavity pleural space. Fluid accumulating in the chest can cause shortness of breath.

Treatments are available to drain the fluid from your chest and reduce the risk that pleural effusion will occur again. Cancer that spreads to other parts of the body metastasis.

Lung cancer - Wikipedia

Lung cancer often spreads metastasizes to other parts of the body, such lung cancer pathophysiology the brain and the bones. Never smokers Defined as people who smoked fewer than cigarettes in their lung cancer pathophysiology.

Environmental exposure A number of environmental risk factors have been identified, most of which relates to occupational exposures such as asbestos, tar, soot, and a number of metals such as arsenic, chromium, and nickel.


Air pollution has also been linked to increased risk of lung cancer. Indoor radon, a radioactive gas that percolates up soil and becomes concentrated inside buildings, have been posed as a significant risk factor for lung cancer.

Smoking potentiates the effect of a number of lung cancer pathophysiology lung carcinogens e.